JRD UPDATES

STATEMENT 24th April 2008
All enquiries regarding JRD or JRD tests should be dealt with through your Vet and/or DOGenes Inc. directly - http://www.dogenes.com
David Payne

What does this DNA test actually tell the breeder?

The DNA test results are reported as follows:

a) Carrier (one copy of the JRD mutation)

b) Homozygous mutant allele = Homozygote (two copies of the JRD mutation)

c) Clear.

With a & b results above – the animal is also "potentially affected" by JRD.

CARRIERS of this mutation can be bred to a clear. In this case, approximately 50% of the offpsring will be clear of the mutation.
Individuals with two copies of the gene (homozygous mutant allele = homozygote), breeding a homozygote to a clear will produce ALL carriers.

TO CONTROL THIS DISEASE IN THE GSD BREED -
ALL CARRIERS SHOULD BE PUBLISHED - AND THEIR PEDIGREES
THEN WE CAN TEST THEIR PARENTS, SIBLINGS & OFFSPRING

GSD JRD DNA TESTS UK - CARRIERS
(ONE COPY OF THE MUTATION)

PRINTED HERE WITH PERMISSION OF THE OWNERS

NIKONIS ASTI - PEDIGREE
NIKONIS ABI - (LITTER SISTER TO ASTI)

GSD JRD DNA TESTS UK - "HOMOZYGOTE" CARRIERS
HOMOZYGOUS FOR A MUTANT ALLELE
(TWO COPIES OF THE MUTATION)

PRINTED HERE WITH PERMISSION OF THE OWNERS

NIKONIS ANNABELLE (LITTER SISTER TO ASTI)
NIKONIS AMARA (LITTER SISTER TO ASTI)

PLEASE VISIT THE FOLLOWING WEBPAGES

http://www.videxgsd.com/juvenile_renal_dysplasia_DNA_test.htm

http://www.bakalo.com/health/RD.htm

http://www.danemist.com/renaldisease.html

http://www.neaa.net/juvenile_renal_dysplasia.shtml